MOLECULAR MECHANISM OF SOME GENRES OF ESCHERICHIA COLI ON HUMAN MUCOSAL EPITHELIUM

Abstract

Escherichia coli pathology has always been of interest to researchers due to its severity and rapid infectivity. Based on the mode of infection and toxicity, E. coli is divided into different groups. Clarified knowledge of the pathogenic mechanisms of each group of E. coli is vital in the development of appropriate and effective therapies. This review provides essential information on the infectious and toxic pathways of some common E. coli groups, including Enterohemorrhagic E. coli (EHEC), which causes diarrhea, hemorrhage, and hemolytic urea syndrome; Enteroinvasive E. coli (EIEC), which causes dysentery, small bowel movements, and bloo  dy mucus; Enteroaggregative E. coli (EAEC), which causes intestinal aggregation and the formation of biofilm covering bacterial biomass; Enterotoxigenic E. coli (ETEC), which produces enterotoxins, causing diarrhea; and adherent E. coli (DAEC) causes acute diarrhea in children.