RISK FACTORS OF AUTISM SPECTRUM DISORDER IN CHILDREN FROM 24 TO 60 MONTHS OF AGE IN TUYEN QUANG

Abstract

This study aims to analyze some risk factors of autism spectrum disorder in children aged 24 to 60 months in Tuyen Quang. The case-control study was conducted on 60 children with autism spectrum disorder and 120 children without autism spectrum disorder aged from 24 to 60 months old in Tuyen Quang from 2022 to 2023. Autistic children were diagnosed according to DSM-IV criteria and the level of autism was classified according to the Child Autism Rating Scale (CARS scale). In addition, the children without autism or other developmental disorders who have the same sex, age, and geographic location were selected in a ratio of 1:2 as the control group. The study results showed that the risk factors for autism in children aged 24 to 60 months in Tuyen Quang were identified as mothers giving birth to children aged 35 years or older, adjusted OR = 3.19 (95% CI 1.01–10.4), (p=0.048) and pathological neonatal jaundice, adjusted OR = 7.23 (95% CI 11.7 – 44.79), (p=0.034).