Wound-healing and anti-inflammatory activities of Anoectochilus formosanus Hayata

Abstract

    Anoectochilus formosanus Hayata is proved to have remarkable pharmacological values such as immune enhancement, liver protection, anti-hyperglycemic and anti-inflammatory activities. A number of studies used various extracts to gain insights into the bioactivities of A. formosanus. Here, we evaluated the in vitro wound-healing activity of the polysaccharide-containing extract (AWE) and anti-inflammatory effect of the ethanol extract (AEE) of cultured A. formosanus. The AWE at the concentration of 100 μg/mL promoted wound recovery in human fibroblasts after 16 hours of treatment. Meanwhile, the AEE showed anti-inflammatory activity using RAW 264.7 cells model based on NO production assay. These results will be a premise for further in vivo studies.