Study on phytochemical and antioxidant effects of leaf extract from Vitex rotundifolia L.f in Ninh Thuan province
Abstract
Recent research has demonstrated that the plant Vitex rotundifolia, which is listed as an endangered and should be preserved species in the province of Ninh Thuan, has estrogen-like effects as well as antioxidant and anti-cancer capabilities. Therefore, the purpose of this study is to compare descriptive observational data with published data in order to assess the phytochemical components of Vitex rotundifolia leaves. The Ciulei technique was used to analyze the phytochemical elements of the leaves. Additionally, the Folin-Ciocalteu and DPPH techniques were used to assess the total polyphenol content and antioxidant activity of the leaf extracts. The findings demonstrated that the preliminary phytochemical composition of Vitex rotundifolia leaves was rich in natural chemicals and that the botanical properties of the leaves were comparable with the reference materials. The amount of polyphenol components was found to be (53.44 ± 0.01) μg GAE/mg with ethanolic extract and (41.93 ± 0.03) μg GAE/mg with aqueous extract. The IC50 (inhibition concentration) values for ethanolic extract and aqueous extract were (58.99 ± 0.02) µg/mL and (136.24 ± 0.03) µg/mL, respectively, demonstrating the considerable antioxidant activity. According to the research, Vitex rotundifolia is a potential therapeutic plant with a high concentration of antioxidant chemicals.
