Study on phytochemistry screening and bioativities testing on Ethanol extract of Melastoma dodecandrum Lour. Melastomaceae

Abstract

     This study aimed to investigate the chemical composition and biological activities of Melastoma dodecandrum Lour. (Melastomaceae) – a medicinal herb, through its 80% ethanol extract. A preliminary phytochemical analysis was performed using an adapted version of the Ciuley method developed by the University of Medicine and Pharmacy, Ho Chi Minh City. The total extract was obtained via 80% ethanol extraction at room temperature. The anti-diabetic potential of the extract was evaluated through inhibition of the α-glucosidase enzyme, while anti-inflammatory and antioxidant activities were assessed using the DPPH radical scavenging model. The findings contribute novel information about Melastoma dodecandrum, highlighting its potential in disease prevention and treatment. The phytochemical screening confirmed the presence of chemical compounds existing in this plant, supporting its anti-diabetic, anti-inflammatory, and antioxidant properties.