Preparation of Cinnamon Toothpaste

Abstract

     Cinnamon oil is extracted from the bark of cinnamon trees (Cinnamomum spp.) which has good antimicrobial activities and is considered a substitute for synthetic antibacterial agents. Based on abundant domestic raw material supply of cinnamon, toothpaste containing cinnamon oil was formulated to prevent tooth decay without using fluoride. By using a simple mixing method, in addition to changing the ratio of thickeners and foaming agent, a base-paste having suitable physical and foaming ability was prepared from 19 % calcium carbonat, 20 % sorbitol 20 %, 1.2 % sodium lauryl sulfate, 1 % carboxymethyl cellulose, 2 % xanthan gum, 3 % glycerin, 0.15 % methyl paraben, 0.1 % aspartame and distilled water adding up to100 %. The base-paste was mixed with Cinnamon oil at concentrations of (1, 2, 3, 4 and 5) % to find the suitable quantity of the active ingredient. The 5 formulations were compared on 3 factors: smell; in vitro antibacterial and antifungal activities on strains of MRSA, MSSA, Candida albicans and phase stability over 6 cycles of thermal shock. The most optimal formula that was chosen contained 2 % Cinnamon oil. The final Cinnamon toothpaste meets the requirements for organoleptic properties, hygiene and safety criteria and physicochemical properties according to TCVN 5816:1994.