DETERMINATION OF SALBUTAMOL IN MEAT SAMPLES WITH GC-MS METHOD

Abstract

The optimal conditions for determination of salbutamol in meat samples by GC/MS method with Agilent 7890N system, MSD 5975C, HP – 5MS have been investigated. Th parameters for the column oven, injector, detector, limit of detection (LOD), and limit of quantitation (LOQ), recovery performance, conditions of sample processing methods have been also examined. The results of the survey were obtained with the scanning mode: SIM; program heat: 120 ºC (0,1 min), increase 15 ºC/min to 245 ºC, increase 30 ºC /min to 300 ºC for 10 minutes; injection mode: splitless; LOD = 0.12 ppb, LOQ = 0.41 ppb, linear range from 10 ppb to 200 ppb, LOD and LOQ on the sample were 0.018 ppb and 0.049 ppb, respectively, and the recovery of method: 100.7 %.
Key words: Salbutamol, Salbutamol – d3, GC/MS, meat samples, SIM.