Study on trend of antibiotic resistance of E. coli bacteria during production cycle of colored feather chickens in some localities of Viet Nam

Abstract

Antimicrobial resistance (AMR) in animal husbandry, in general and in poultry industry, in particular is one of the high threaten problems for public health. The study was conducted to determine the level of antibiotic resistance at different times in a poultry production cycle. 60 medium scale farms (2,000-5,000
chickens/farm) of the colored feather broiler farms (30 farms in Luc Nam district, Bac Giang province and 30 farms in Ba Vi district, Ha Noi City) were selected for the study. At each farm, the research team conducted four visits at four different times in the production cycle including 7-12 days old chickens, 30
40 days old chickens, 90-100 days old chickens and chickens before the last one was sold. One healthy chicken cloacal swab was collected in each visit. A total of 237 samples was collected for identifyingE. coli. The studied result showed that there were 232 E. coli strains isolated and they were tested for antimicrobial susceptibility to assess the AMR at farm level during chicken production cycle. The result of AMR evaluation showed that AMS at high level of the E. coli strains was to ampicillin, sulfonamides, tetracycline, chloramphenicol, streptomycin during a production cycle. 54 out of 232 (23.3%) of E. coli isolates were resistant to colistin. Of which, 21 isolates were co- resistant to colistin and 3rd, 4th generation cephalosporine. Furthermore, in 1 farm occurred E. coli strains that were co-resistant to colistin and  3rd and 4th generation cephalosphorine at all sampling times 1, 2, and 3. The resistance level of the 3rd generation cephalosporines and ciprofloxacin was grandually significant decreasing in different chicken ages in both study sites. Further research is needed on poultry diseases and the habit of using antibiotics to prevent and treat diseases in chickens during the production cycle to clarify and find a basis for reducing the level of resistance to these antibiotic types of E. coli strains. Since then, we continue to recommend and propagate the use of antibiotics carefully in livestock production. At the same time, continue to strengthen management measures to closely monitor the use of important antibiotic groups for preventing and treating animals.