Investigation on some biological characteristic of Porcine circovirus type 2 (PCV2) strains after lyophilization

Abstract

The objective of this study aimed at investigating some biological characteristics of PCV2 strains after lyophilization. By using IFA method, the viable titers of PCV2 were in the range of 104,5 TCID50/0,1ml to 105,25 TCID50/0,1ml. These titers were lower than the viral titers before lyophilization. These titers, however were still adequate for vaccine production. Result of experimental infection for pigs with the reconstituted viruses indicated that 3 PCV2 strains were able to induce specific immune responses. Of which, sero-conversions occurred within 7 to 14 days after infection.