Some biological features of Mycoplasma hyopneumoniae strain - PV3952

Abstract

The objective of this study aimed at investigating some biological features of the M. hyopneumoniae
strain - PV3952 so as to use for vaccine development against the pneumonia in pigs. The genetic
features, adaptable ability and growth on Friis medium, the pathogenicity as well as ability to
induce immune response in pigs of the M. hyopneumoniae strain - PV3952 were detected, by
using molecular techniques, serological test and experimental infection in pigs. The studied results
showed that the genetic features of M. hyopneumoniae strain - PV3952 were similar to those of other
M. hyopneumoniae strains isolated in Viet Nam. This bacteria also adapted and grew well on the
Friis medium and stability from the 5th generation onwards. The result of pathogenic tests showed
that, the M. hyopneumoniae strain - PV3952 was highly virulent bacteria strain in the experimental
pigs, and its pathogenicity was not changed through many passage inoculation generations on Friis
medium. Moreover, the M. hyopneumoniae strain - PV3952 was able to induce strongly immune
response against porcine pneumonia.