In vitro antibacterial and pharmacological characteristics of Rhodomyrtus tomentosa and Cinnamomun zeylanicum leaf extract

Abstract

This study was conducted with the goal of investigating the extraction method, antibacterial and antioxidant activity of Rhodomyrtus tomentosa and Cinnamomun zeylanicum leaf extracts. The studied results showed that the active ingredients in the extract were clearly separated by thin-layer chromatography (TLC) and the presence of rhodomyrtone in R. tomentosa leaf
extract and cinnamaldehyde in C. zeylanicum leaf extract. R. tomentosa leaf extract presented antibacterial activity against Staphylococcus aureus (13.1 mm) but it was not effective against Salmonella typhimurium. C. zeylanicum leaf extract did not show antibacterial activity on both S. aureus and S. typhimurium. At a dilution concentration of 1/2 of the R. tomentosa crude extract could completely inhibit S. aureus. The studied results showed that R. tomentosa and C. zeylanicum leaf extracts could replace antibiotics to treat disease caused by S. aureus. But in vivo investigation for using C. zeylanicum leaf extracts in disease treatment is needed to make a more accurate assessment.