Several clinical signs and hematological parameters in canine Parvovirus infection

Abstract

In this study, investigation on the change of several clinical signs and hematological parameters of the Parvovirus infection dogs was carried out. The blood samples of dogs expecting infection with Parvovirus with the typical symptoms was collected for diagnosis by CPV quick test technique, and then 30 positive dogs with this disease and 30 healthy dogs were selected for
determing the hematological parameters. The result of study indicated that the typical symptoms, included lethargy, bloody diarrhea, vomitting, anorexia, weight loss, fever. The body temperature, respiratory and heart rate of the CPV infection dogs showed higher than that of the healthy dogs. The hematological parameters of the CPV infection dogs were changed significantly in comparison to that of the healthy ones. The parameters of red blood cells, such as: the number of erythrocytes, hemoglobin content, average hemoglobin concentration, amount of erythrocytes, average volume of erythrocytes and red blood cell resistance of the infection dogs were decreased in comparison with the control dogs (P<0.05). In the disease dogs, the parameters of white blood cells, such as: the number of leukocytes decreased as compared to the control dogs (P<0.05) and its formula was changed, the number of neutrophils increased, the monocytes, eosinophils and basophils were changed invisibly, but lymphocytes decreased. The biochemical parameters in the dogs infected with Parvovirus were changed. The total protein of serum, albumin volume and A/G ratio decreased as compared with the control dogs (P<0.05), and the formula of corpuscular globulins were also changed, of which, α-globulin and γ-globulin increased. GOT and GPT enzymes level and uretic volume increased, in case of creatinin, blood sugar level and alkalinity reserve decreased in comparison with the healthy dogs. The result of this study distributes an important base in primary diagnosis of canine Parvovirus disease.