Applying pharmaceutical products derived from Rhodomyrtus tomentosa and Lactuca indica L. for diarrheal prevention and treatment in chicken

Abstract

This study was performed to produce pharmaceutical products from Rhodomyrtus tomentosa and Lactuca
indica L. herbal plants, so as to replace antibiotics in diarrhea prevention and treatment in chickens. The
studied results showed that 2 herbal plants were extracted by different solvents and obtained the products
that could inhibit the development of Escherichia coli (E. coli). Among the solvents were used to extract the
above herbal plants, ethanol 70% was the best as the product obtained from this solvent was the strongest
in inhibiting E. coli (showing the largest inhibitory zone diameters: 27.31 ± 2.08 mm for Rhodomyrtus
tomentosa extract product and 29.21 ± 2.28 mm for Lactuca indica L. extract product). In prophylactic and
therapeutic experiments for diarrhea in chickens, combining 75% of Rhodomyrtus tomentosa extract product
with 25% of Lactuca indica L. extract product had given the highest efficacy. For diarrheal prevention, mixing
50 mg (2 herbal extract products) in 1 kg of feed, to feed the experimental chickens was the best fomular,
due to only 4% of chickens in experimental group were infected with diarrhea, while 20% of chickens in
the control group were infected with diarrhea. On trial treatment, the fomular of mixing 2000 mg (2 herbal
extract product) in 1 kg of feed, to feed the disease chickens, as a result, 80% of chickens were recovered.