Treatment Outcomes and the Relevant Factors of Patients with Acute Ischemic Stroke treated at Thong Nhat Hospital in Ho Chi Minh City

Abstract

Background: Acute ischemic stroke (AIS) is a leading cause of disability and mortality globally. Treatment outcomes for AIS patients can vary widely based on several factors, including demographic characteristics, clinical presentations, and access to timely interventions.

Objective: This study aims to evaluate the treatment outcomes of AIS patients at Thong Nhat Hospital and identify relevant factors influencing these outcomes.

Method: A retrospective cross-sectional study was conducted, including AIS patients admitted to Thong Nhat Hospital from Jan, 2023 to March, 2024. Data on patient demographics, clinical presentations, risk factors, treatment methods, and outcomes were collected and analyzed. Key outcomes included modified Rankin Scale when discharged and after 90 days of treatment and the related factors which can affect the recovery prognosis.

Result: Among the 158 AIS patients studied, 79 patients received reperfusion therapy while 79 others did not. Significant differences in treatment outcomes were observed based on sociodemographic characteristics, clinical symptoms, laboratory tests results and time to treatment. Patients who received reperfusion therapy demonstrated better functional outcomes (mRS scores) at discharge and 3 months post-treatment compared to those who did not. Additionally, factors such as age group (OR 22.688; 95% CI 1.293 – 398.198, p = 0.033) and initial NIHSS score (OR 2.281; 95% CI 1.103 – 4.715, p = 0.026) were found to influence treatment outcomes significantly.

Conclusion: The study highlights the critical role of timely and appropriate treatment in improving outcomes for AIS patients. Identifying and understanding the relevant factors influencing these outcomes can help optimize treatment protocols and enhance patient care at Thong Nhat Hospital. Further research is warranted to explore the long-term effects of these factors and refine patient management strategies for better clinical outcomes.