OPTIMIZATION OF TOTAL PHENOLIC AND TOTAL FLAVONOID EXTRACTION CONDITIONS FROM LEAVES OF LAUNAEA SARMENTOSA USING THE RESPONSE SURFACE METHODOLOGY

  • Nguyen Tan Thanh
  • Tran Dinh Thang
  • Nguyen Thi Huyen
  • Tran Thi Thu Ha

Abstract

The Central composite design (CCD) of response surface methodology (RSM) was used to investigate the effects of three factor as extraction temperature (°C), extraction time (min) and ethanol concentration (%) of Launaea sarmentosa leaves on the responses: total phenolic content (TPC) and total flavonoid content (TFC). The optimal conditions obtained from response RSM were 90% v/v for
the solvent ratio, 54°C for extraction temperature and 110min for extraction time. The experimental values of TPC and TFC were 318.85±0.32 mgGAE/g, 8.21±0.14 mgCE/g.

điểm /   đánh giá
Published
2021-01-20
Issue
Vol. 25 No. 2 (2020)
Section
ARTICLES