Characteristics of using antibiotic on surgical patients under the program at Department Gastrointestinal and Hepatobiliary Surgery, Bach Mai Hospital

https://doi.org/10.52322/jocmbmh.120.10

Abstract

Objectives: The aim of this study was to assess the current situation of antibiotic use among patients who had surgery indicated at the Department of Gastrointestinal and Hepatobiliary Surgery, Bach Mai Hospital.

Material and Methods: A cross-sectional study was applied selecting all medical records of patients having surgery indicated in December 2020 at the Department of Gastrointestinal and Hepatobiliary Surgery, Bach Mai Hospital.

Results: 171 medical records of the patients were examined. Majority of the patients from 16- 66 years (80.1%). 50.3%) the patients had comorbidity, mainly high blood pressure, liver diseases, and stomach diseases. The main risk factors of surgical site infection was ASA score ≥3. On the day of the surgery, 27.5% of patients were given the first antibiotic dose within 120 minutes before the time of skin incision. The antibiotic regimen of choice was mainly cefoxitin and cefoperazon/ sulbactam used alone or in combination with metronidazole or ciprofloxacin. Of which, only cefoxitin regimen alone was evaluated in accordance with the antibiotic prophylaxis suggestion of the American Society of Health System Pharmacists (ASHP) guidelines, accounting for 48.0%. Only 11.1% patients were stopped antibiotic within 24 hours after the surgery, 59.1% of them were given antibiotics last for 4 days after the surgery.

Conclusions: This study described the characteristics, and situations of using antibiotics of the patients had surgery indicated at the Department of Gastrointestinal and Hepatobiliary Surgery, Bach Mai Hospital. The findings provided important information for the implementation of antibiotic prophylaxis regimens in the Department in collaboration with clinical pharmacists in the near future.